Thalidomide for Anorexia

Thalidomide was used in the 1960s as an anxiolytic and antiemetic agent for pregnant women and was withdrawn from use because of its teratogenic effects. Because of its antiangiogenic properties, it has resurfaced as an antineoplastic drug and currently is indicated for the treatment of multiple myeloma.Thalidomide reduces the production of tumor necrosis factor alpha.