Clinical Challenges

Chemotherapy-Induced Infertility in Patients With Testicular Cancer

Brittany R. Bradford

testicular neoplasms, fertility, infertility
ONF 2011, 39(1), 27-30. DOI: 10.1188/12.ONF.27-30

A 29-year-old Caucasian married man, Mr. A, is the father of a 1-year-old daughter and is a successful tax attorney who maintains a healthy lifestyle. While performing a testicular self-examination, Mr. A noticed a small, fixed mass in his left scrotum. After medical workup, biopsy, and consultation, a left orchiectomy and retroperitoneal dissection were recommended. Pathology revealed a nonseminoma germ cell testicular tumor, pT4, N4, M-positive; with tumor invading the scrotum; vascular and lymphatic invasion; and a solitary lung lesion noted on computed tomography scan. No additional metastatic lesions were found on bone scan or magnetic resonance imaging. Biopsy confirmed the metastatic lesion in the lung. Postoperatively, Mr. A was scheduled to receive four cycles of bleomycin, etoposide, and cisplatin (BEP), a standard treatment for testicular germ cell cancer.

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