ONS Fundamentals of Chemotherapy and Immunotherapy Administration™



The ONS Fundamentals of Chemotherapy and Immunotherapy Administration course provides nurses with the tools to understand how antineoplastic medications are used in cancer and non-cancer treatment, the effect of medication-related toxicities, and evidence-based recommendations to manage and treat these toxicities. The content of this course is aligned with the ONS Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition).

This expanded and revised course has been designed to include new antineoplastic therapies approved since the prior version, as well as new evidence relating to nursing care of the patient receiving these therapies.

Orange background box with white text that says "This ONS course is designated as an Optimized Learning Experience, combining clinical expertise with best practices for adult learning.Learners may experience detailed medical illustrations, strategically placed knowledge checks, and real-world case studies with interactive scenarios."


Are you new to antineoplastic administration? 

Are you new to administering antineoplastic medications and looking to learn about these therapies? 

Do you care for patients receiving antineoplastic therapy? 

Do you want to earn a ONS Fundamental Chemotherapy Immunotherapy Provider Card?  

This course will provide you with a foundational level of knowledge about antineoplastic therapy, how they are used in cancer and noncancer treatment, and the effects on the patients who receive them.   

Do you need a more advanced-level of knowledge?  

Is administering these medications part of your daily practice? 

Do you have nursing practice experience of six months or more? 

Consider the advanced level ONS/ONCC Chemotherapy Immunotherapy Certificate™ course for a deeper dive into content along with advanced-level topics.  

Are you new to oncology and want to learn about oncology basics in addition to the fundamentals of antineoplastic therapy? 

Consider the ONS Foundations of Oncology Nursing Practice Bundle™. This bundle includes three foundational courses: ONS Cancer Basics™, ONS Cancer Biology™, and ONS Fundamentals of Chemotherapy Immunotherapy Administration™. 


This course includes the following new features: 

  • New content: Hypersensitivity response, safe handling of hazardous drugs, and expanded content on genomics are now included in the course. Health equity is discussed with information on diversity and inclusion principles. The latest guidelines and recommendations for treatment, symptom management, and survivorship are also included. 
  • New design: The course places the nurse in case studies to make clinical decisions and includes knowledge checks that place the nurse in real-world scenarios. The overall design and features provide an optimized learning experience to better prepare the learner to apply the information in the clinical setting.  
  • Drug monographs: The course provides printable drug-specific resources that contain bite-sized information on the most common antineoplastic medications. These can be used for reference after the course to guide your application of the information to your practice.  


  • 180 days of access to the self-paced content 
  • All course registrants will receive a digitally accessible version of the ONS Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition). You can access the e-book while navigating the course or at any time via your ONS dashboard or the Bookshelf™ mobile app. Your e-book will remain accessible after the course has ended through Bookshelf™, ONS's digital rights management platform, which houses ONS e-book purchases.  
  • This course is available on demand. Instructions on how to immediately access the course will be sent in an automatically generated email.  

What Will I Receive at the Completion of This Course 

Upon successful completion of the course post-test with a score of 80% or higher and completion of the course evaluation, you will receive:  

Course Topics

  • Chemotherapy, hormone therapy, targeted therapy, and immunotherapy
  • Principles of administration
  • Approaches to treatment
  • Complications of antineoplastic infusion
  • Safe handling of hazardous drugs (donning and doffing procedures)
  • Caring for the patient receiving antineoplastic therapy
  • Dose-limiting toxicities
  • Routes of administration

Expected Outcomes

Upon completion of this activity, the learner will demonstrate fundamental-level knowledge of antineoplastic administration by passing the post-test with score of 80% or higher. 

Target Audience

This course is designed to meet the educational needs of nurses and other healthcare professionals new to oncology who provide care for patients receiving antineoplastic therapy and/or those preparing for a nursing practice that includes administration for non-oncology indications.   

ILNA Breakdown

No more than 10 total ILNA points may be claimed for the program.  Up to 0.5 points may be applied to Care Continuum (AOCNP) OR Psychosocial Dimensions of Care (OCN, AOCNP, CBCN, BMTCN). Up to 10 points may be applied to Oncology Nursing Practice (OCN, CBCN) OR Treatment (AOCNP). Up to 7 points may be applied to Treatment (OCN, CBCN). Up to 3 points may be applied to Symptom Management, Palliative Care, Supportive Care (OCN). Up to 1.0 point may be applied to Oncologic Emergencies (OCN, AOCNP, CBCN) OR Transplant Process and Infusion (BMTCN) OR Professional Practice/Performance (BMTCN).